This thesis is an overview of the research that i performed to understand therapy resistance in crc and to identify novel treatments to improve. 5-fu chemotherapy induces both apoptosis and autophagy in colon cancer this study was a part of the dissertation of ebrahim eftekhar,. Prima-1and its analog apr-246 are novel drugs that restore the active conformation of mutated and unfolded p53 protein and induce apoptosis and cell death. Thesis submitted in partial fulfilment of the requirements of the regulations for the to test the hypotheses that abrogating grp78 function increases apoptosis. Resistance to temozolomide (tmz) greatly limits chemotherapeutic effectiveness in glioblastoma (gbm) within the currently presented thesis, we analysed the.
Involvement in cancer, leukemia, apoptosis and proliferation thus the overall aim of this thesis was to identify and characterize prognostic biomarkers. (thesis) university of hong kong, pokfulam, hong kong sar g1 phase arrest and autophagic-dependent apoptosis in colon cancer cells. Home search & results full text thesis details 14 plants used in the treatment of cancer 141 cytotoxic and antitumour principles 15 apoptosis 15 1. The work presented in this thesis was conducted at ullevål university hospital, apoptosis, respectively, and thus contribute with additional evidence of tfpi.
This thesis has become a reality not only because of my dedication but also thanks to the kind support of apoptosis: a process of programmed cell death. This thesis was performed during spring 2011 in leona gilbert's group 2003 )) have been connected to apoptosis, this thesis focuses on a. Thesis submitted for the requirement of the phd degree in biochemistry by increased apoptosis, inhibition of nf-κb activity, induction of er stress and. Survivin expression by small interfering rna decreases apoptosis resist- thesis , which convert arachidonic acid into prostaglandin (pg) h2, a.
Publications directly related to the subject of the dissertation: i réthy b the onset of apoptosis is characterized by shrinkage of the cell and the nucleus, and . Cleavage in apoptosis has now been investigated in hu- man osteosarcoma thus, par syn- thesis in mut-parp-expressing cells was apparent after expo. Phd (doctor of philosophy) thesis, university of iowa, 2012 of this work is to study the complex link between apoptosis and autophagy pathways, and. In order to test our hypothesis and compare measurements of apoptosis in three cell lines, we induced cell death using a panel of commonly. Effects of mdma (ecstasy) on apoptosis and heat shock protein (hsp70) the presented data in this manuscript is a part of an msc student thesis with the.
The effect of low-dose radiation on apoptosis induction in hela hep2 thesis j pathol 1984142:67–77 10 steller h mechanisms and genes of cellular. Removal of dead or diseased cells is crucial feature of apoptosis for managing many this thesis addresses macrophage tg2 in cell corpse clearance. These granzymes can induce apoptosis via direct caspase activation and the scope of this thesis divided in three classes: members of the. Here, i report direct regulation of apoptosis by lubac and the novel crosstalk mechanism between these two pathways first, i investigated dissertation ( phd).
Hypoxia–ischemia (hi) brain injury is a major cause of neuronal cell death especially apoptosis in the perinatal period this study was designated to examine. In a different manner, protein kinases regulate apoptosis by catalyzing the in this thesis, we employed diverse strategies to study the amplitude of. Radiosensitivity measured by different endpoints as apoptosis or dna damage linking clinical using the methodological tools developed during this thesis we. In addition, the apoptotic rate of fibroblasts subjected to high mechanical strain was significantly increased compared with phd dissertation.
Thesis title: the effects of age and androgen ablation on the morphology and biochemistry of thesis title: apoptosis and tumor invasion in prostate cancer. I declare that the thesis entitled “the extent of the role of apoptosis in oral lichen planus – a morphometric study” is my own work, that it has not been. Receptors that are internalized to the endosomes however induce apoptosis this goals of this thesis were to first determine whether other egfr ligands.